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Home/Compounds/Pharmaceutical Intermediate/2-Deoxy-2,2-difluoro-alpha-D-erythro-pentofuranose 3,5-dibenzoate 1-methanesulfonate
C20H18F2O8S
456.4 g/mol
Pharmaceutical Intermediate

((2R,3R,5R)-3-(Benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate

CAS134877-42-2
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate

This compound is a difluorinated tetrahydrofuran derivative featuring two benzoate ester groups and a methylsulfonyloxy leaving group, configured with defined stereochemistry. It serves as a pharmaceutical intermediate for the synthesis of nucleoside analogs in research and development settings.

Pharmaceutical intermediate for nucleoside analog synthesisResearch reagent for oligonucleotide chemistry

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 134877-42-2

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Identifiers
IUPAC Name

[(2R,3R,5R)-3-benzoyloxy-4,4-difluoro-5-methylsulfonyloxyoxolan-2-yl]methyl benzoate

InChIKey

LIAQHZDWFACWFK-GPMSIDNRSA-N

SMILES

CS(=O)(=O)O[C@@H]1C([C@@H]([C@H](O1)COC(=O)C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)(F)F

Synonyms (9)
  • Gemcitabine impurity 1