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Home/Compounds/Pharmaceutical Intermediate/Doxorubicin-SMCC
C39H42N2O14
762.8 g/mol
Pharmaceutical Intermediate

Doxorubicin-SMCC

CAS400647-59-8
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate

Doxorubicin-SMCC is a pharmaceutical intermediate used in the manufacturing of antibody-drug conjugates (ADCs). This compound consists of a doxorubicin core linked to a maleimide-containing crosslinker, enabling targeted conjugation to antibodies.

Pharmaceutical intermediate for antibody-drug conjugate manufacturingResearch reagent for ADC development and synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

4-[(2,5-dioxopyrrol-1-yl)methyl]-N-[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]cyclohexane-1-carboxamide

InChIKey

OTQOQHVWNBKSGU-SAJDXUNTSA-N

SMILES

C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)NC(=O)C6CCC(CC6)CN7C(=O)C=CC7=O)O

Synonyms (5)
  • Doxorubicin-SMCC