C11H19NO4
229.27 g/mol
Pharmaceutical IntermediateWarning
(2S)-1-[(tert-butoxy)carbonyl]piperidine-2-carboxylic acid
CAS26250-84-0EC628-510-4
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate
This compound is a protected proline derivative used as an intermediate in peptide synthesis. Its structure features a tert-butoxycarbonyl (Boc) protecting group on the nitrogen and a free carboxylic acid, making it valuable for solid-phase and solution-phase peptide assembly.
Pharmaceutical intermediate for peptide synthesisBuilding block in research and development of peptide-based compounds
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 26250-84-0
Related Compounds
StrongStructure SimilarSimilarity 0.90
N-Boc-D-proline
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pharmaceutical intermediate
StrongStructure SimilarSimilarity 0.90
Boc-L-Proline
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ReferenceSame Category
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ReferenceSame Category
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pharmaceutical intermediate
ReferenceSame Category
2-Amino-2,3-dimethylbutanoic acid
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pharmaceutical intermediate
Referencestereoisomer of
(R)-(+)-N-Boc-2-piperidinecarboxylic acid
CAS28697-17-8
pharmaceutical intermediate
Referencestereoisomer of
N-Boc-2-piperidinecarboxylic acid
CAS98303-20-9
pharmaceutical intermediate
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-2-carboxylic acid
InChIKey
JQAOHGMPAAWWQO-QMMMGPOBSA-N
SMILES
CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)O
Synonyms (38)
- (L)-N-Boc-Pipecolic acid
- (S)-1-N-Boc-Pipecolinic acid
- (S)-N-Boc Pipecolic Acid
- 1-Boc-L-pipecolic Acid
- BOC-HPro-OH
- Boc-L-Pipecolic acid
- Boc-Pip-OH
- N-BOC-L-PIPECOLIC ACID
- N-Boc-L-pipecolinic acid
- boc-homopro-oh
- boc-l-pip-oh