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Home/Compounds/Pharmaceutical Intermediate/Boc-L-Proline
C10H17NO4
215.25 g/mol
Pharmaceutical IntermediateWarning

Boc-L-proline

CAS15761-39-4EC239-848-3
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Boc-L-proline is a protected amino acid derivative commonly used as a building block in peptide synthesis. Its primary significance lies in providing a stable, easily removable protecting group for the proline residue during solid-phase or solution-phase peptide assembly.

Protected amino acid for peptide synthesisBuilding block for pharmaceutical intermediate manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.90

(S)-1-Boc-piperidine-2-carboxylic acid

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(R)-(+)-N-Boc-2-piperidinecarboxylic acid

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StrongStructure SimilarSimilarity 0.90

N-Boc-2-piperidinecarboxylic acid

CAS98303-20-9

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StrongStructure SimilarSimilarity 0.88

N-(tert-Butoxycarbonyl)prolylproline

CAS15401-08-8

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ReferenceSame Category

N-Boc-piperidine-2-methanol

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ReferenceSame Category

1-Boc-2-piperidinecarbaldehyde

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ReferenceSame Category

4-Bromo-1-methylpyrazole

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ReferenceSame Category

Resmetirom Impurity 37

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Related Reading

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for Boc-L-proline (CAS 15761-39-4) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

InChIKey

ZQEBQGAAWMOMAI-ZETCQYMHSA-N

SMILES

CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O

Synonyms (53)
  • BOC-PRO
  • (S)-Boc proline
  • (S)-N-Boc-proline
  • Boc-L-Pro-OH
  • Boc-L-proline
  • Boc-Pro-OH
  • Boc-Pro-OH, >=99.0% (T)
  • Boc-proline
  • N-BOC-(S)-PROLINE
  • N-BOC-proline
  • N-Boc-L-Pro-OH
  • N-Boc-L-proline
  • N-t-butoxycarbonylproline
  • N-tert-Butoxycarbonylprolin
  • N-tert-Butoxycarbonylproline
  • boc-(s)-proline
  • boc-prolin
  • t-Boc-l-proline
  • t-butoxycarbonylproline
  • t-butyloxycarbonyl-L-proline
  • t-butyloxycarbonyl-proline
  • tert-Butoxycarbonyl-L-proline
  • tert-Butoxycarbonylproline

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