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Home/Compounds/Pharmaceutical Intermediate/N-Boc-D-proline
C10H17NO4
215.25 g/mol
Pharmaceutical IntermediateWarning

(2R)-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid

CAS37784-17-1EC805-206-1
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

This compound is a protected amino acid derivative of D-proline, featuring a tert-butoxycarbonyl (Boc) protecting group. It is primarily used as a building block in solid-phase peptide synthesis, enabling the incorporation of D-proline residues into peptide chains.

Building block for peptide synthesisProtected amino acid in pharmaceutical intermediate manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.90

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StrongStructure SimilarSimilarity 0.88

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Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name

(2R)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

InChIKey

ZQEBQGAAWMOMAI-SSDOTTSWSA-N

SMILES

CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O

Synonyms (29)
  • (2R)-N-BOC-proline
  • (r)-n-boc-proline
  • Boc-3,4-dihydro-D-proline
  • Boc-D-Pro-OH
  • Boc-D-proline
  • N-ALPHA-T-BOC-D-PROLINE
  • N-Boc-D-Pro
  • N-Boc-D-proline
  • N-T-BOC-D-PROLINE
  • n-boc-(r)-proline
  • tert-butoxycarbonyl-D-proline

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