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Home/Compounds/API/Afatinib Impurity AFT-8
C24H27ClFN5O4
504 g/mol
API

Afatinib Impurity AFT-8

CAS2323570-72-3
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material

Afatinib Impurity AFT-8 is a chemical compound that serves as a reference standard for the active pharmaceutical ingredient afatinib. It is primarily used in pharmaceutical quality control and research to identify and quantify related impurities.

Reference standard for impurity identificationQuality control in pharmaceutical manufacturingResearch compound for analytical method development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.86

N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-3,4-bis(dimethylamino)butanamide

CAS2414260-31-2

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.74

(S)-N1-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-N2,N2-DIMETHYLOXALAMIDE

CAS2223677-66-3

pharmaceutical intermediate

ReferenceSame Category

6,9-Difluoro-11-hydroxy-3,20-dioxopregna-1,4,16-trien-21-yl acetate

CAS2326-26-3

pharmaceutical raw material

ReferenceSame Category

Adagrasib

CAS2326521-71-3

pharmaceutical raw material

ReferenceSame Category

Nalbuphine hydrochloride

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pharmaceutical raw material

ReferenceSame Category

Sulfachlorpyridazine sodium

CAS23282-55-5

pharmaceutical raw material

Referencestereoisomer of

(R)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide

CAS2413212-23-2

pharmaceutical intermediate

Identifiers
IUPAC Name

N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-3-hydroxybutanamide

InChIKey

IQINQKMQCQYKAD-LYKKTTPLSA-N

SMILES

CN(C)CC(CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4)O

Synonyms (7)
  • Afatinib Impurity AFT-8
  • Afatinib impurity 44