Home/Compounds/Pharmaceutical Intermediate/(1R,3R,4R,7S)-3-(4-N-Benzoyl-5-methylcytosin-1-yl)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxy)-1-(4,4'-dimethoxytrityloxymethyl)-2,5-dioxabicyclo(2.2.1)heptane
C48H54N5O9P
875.9 g/mol
Pharmaceutical IntermediateWarning
(1R,3R,4R,7S)-3-(4-N-Benzoyl-5-methylcytosin-1-yl)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxy)-1-(4,4'-dimethoxytrityloxymethyl)-2,5-dioxabicyclo(2.2.1)heptane
CAS206055-82-5EC686-261-7
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate
This compound is a modified nucleoside phosphoramidite building block used in the solid-phase synthesis of oligonucleotides. Its structure features multiple protective groups, including a dimethoxytrityl (DMT) group for 5'-hydroxyl protection and a cyanoethyl phosphoramidite moiety for internucleotide linkage formation.
Oligonucleotide synthesis building blockResearch reagent for nucleic acid chemistry
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 206055-82-5
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ApplicationSame Use
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Safety Reference
Warning
H319Causes serious eye irritation
Identifiers
IUPAC Name
N-[1-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChIKey
XHILZPWJJJDDDY-HXAWEXODSA-N
SMILES
CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)[C@H]3[C@H]4[C@@H]([C@@](O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
Synonyms (11)
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