This compound is a modified phosphoramidite building block used in oligonucleotide synthesis, specifically designed for incorporating locked nucleic acid (LNA) residues into synthetic DNA or RNA sequences. It features a DMTr protecting group, a benzoyl-protected cytosine base, and a cyanoethyl phosphoramidite moiety, enabling automated solid-phase synthesis of LNA-modified oligonucleotides for research applications.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 206055-78-9
(1R,3R,4R,7S)-3-(4-N-Benzoyl-5-methylcytosin-1-yl)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxy)-1-(4,4'-dimethoxytrityloxymethyl)-2,5-dioxabicyclo(2.2.1)heptane
pharmaceutical intermediate
(1R,3R,4R,7S)-3-(6-N-Benzoyladenin-9-yl)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxy)-1-(4,4'-dimethoxytrityloxymethyl)-2,5-dioxabicyclo(2.2.1)heptane
research compound
(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
pharmaceutical intermediate
Bz-rC Phosphoramidite
research compound
DSPACER CEP
research compound
6'-chloro-2H-[1,3'-bipyridin]-2-one
research compound
Calycosin 7-O-β-D-glucoside
research compound
4-(4-Methoxyphenyl)butanoic acid methyl ester
research compound
N-[1-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-2-oxopyrimidin-4-yl]benzamide
SSGINSHBUWKRHC-XCHZTBEFSA-N
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@@H](O[C@]1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=CC(=NC6=O)NC(=O)C7=CC=CC=C7
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