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Home/Compounds/Pharmaceutical Intermediate/1-(2,5-Anhydro-4-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-6-deoxy-alpha-L-mannofuranosyl)-4-benzamido-5-methylpyrimidin-2(1H)-one
C49H56N5O9P
890 g/mol
Pharmaceutical Intermediate

5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)

CAS1197033-17-2
Category
Pharmaceutical Intermediate
Compound Class
Amide
Primary Use
Pharmaceutical Intermediate

This compound is a modified nucleoside phosphoramidite designed for use in oligonucleotide synthesis. It features a locked nucleic acid (cEt) backbone modification and a dimethoxytrityl (DMT) protecting group, which are important for constructing chemically modified oligonucleotides used in research.

chemical intermediate for oligonucleotide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.79

(1R,3R,4R,7S)-3-(4-N-Benzoyl-5-methylcytosin-1-yl)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxy)-1-(4,4'-dimethoxytrityloxymethyl)-2,5-dioxabicyclo(2.2.1)heptane

CAS206055-82-5

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.76

9-(2,5-Anhydro-4-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-6-deoxy-alpha-L-mannofuranosyl)-N-benzoyl-9H-purin-6-amine

CAS1197033-19-4

research compound

SimilarStructure SimilarSimilarity 0.74

1-(2,5-Anhydro-4-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-6-deoxy-alpha-L-mannofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS1197033-22-9

pharmaceutical intermediate

ReferenceSame Category

(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-((trimethylsilyl)oxy)propyl)azetidin-2-one

CAS1197343-09-1

pharmaceutical intermediate

ReferenceSame Category

Battery Park City Authority

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pharmaceutical intermediate

ReferenceSame Category

1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione

CAS1197377-31-3

pharmaceutical intermediate

ReferenceSame Category

4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile

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pharmaceutical intermediate

Referencesame scaffold

DMTr-LNA-C(Bz)-3-CED-phosphoramidite

CAS206055-78-9

research compound

Identifiers
IUPAC Name

N-[1-[(1S,3R,4R,6S,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChIKey

BDTXILPCBUAYPJ-USFFSJIASA-N

SMILES

C[C@H]1[C@]2([C@H]([C@@H](O1)[C@@H](O2)N3C=C(C(=NC3=O)NC(=O)C4=CC=CC=C4)C)OP(N(C(C)C)C(C)C)OCCC#N)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

Synonyms (6)

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