This compound is a quinazoline diamine derivative used as a pharmaceutical intermediate in the manufacture of afatinib impurity standards. It features a dichlorophenyl substituent and a chiral oxolanyl ether group, with a molecular weight of 390.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 2044709-79-5
N4-(3-chloro-4-fluorophenyl)-7-(((3S)-tetrahydro-3-furanyl)oxy)-4,6-quinazolinediamine
pharmaceutical raw material
(R)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine
pharmaceutical raw material
Desfluoro-N-des(4-dimethylamino-2-en-1-oxo)butyl Afatinib
pharmaceutical raw material
(S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
pharmaceutical intermediate
6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-quinazolinol
pharmaceutical intermediate
Methyl (3R,4S)-1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoate
pharmaceutical intermediate
1-Bromo-3,5-dimethoxybenzene
pharmaceutical intermediate
N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl]-L-lysine
pharmaceutical intermediate
4-N-(3,4-dichlorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine
BWMFVFPCIQVGNU-NSHDSACASA-N
C1COC[C@H]1OC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=C(C=C4)Cl)Cl)N
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