ChemAbout

ChemAbout is a B2B platform where chemical buyers and suppliers discover each other.

Post a purchase requestList your products (for suppliers)
© 2026 ChemAbout
Compound Index|Demand Board|Insights|Exhibitions|Compliance|Help Center|Privacy Policy|Terms of Service|[email protected]
Home/Compounds/Pharmaceutical Intermediate/6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-quinazolinol
C14H10ClFN4O
304.7 g/mol
Pharmaceutical Intermediate

6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-quinazolinol

CAS1449430-53-8
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

This compound is an amino-substituted quinazoline derivative used as a pharmaceutical intermediate in the manufacturing of afatinib-related impurities. It is characterized by the presence of aromatic rings, amine groups, and halogen atoms.

Pharmaceutical intermediate for afatinib impurity preparationResearch reagent for analytical method development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Sourcing 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-quinazolinol?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→

Related Compounds

ApplicationSame Use

(S)-N4-(3,4-Dichlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

CAS2044709-79-5

pharmaceutical intermediate

ReferenceSame Category

7-fluoro-2-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one

CAS1449598-85-9

pharmaceutical intermediate

ReferenceSame Category

N-Boc-L-pyroglutamic acid ethyl ester

CAS144978-12-1

pharmaceutical intermediate

ReferenceSame Category

Ethyl Boc-D-pyroglutamate

CAS144978-35-8

pharmaceutical intermediate

ReferenceSame Category

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic acid 1-methyl ester

CAS145038-52-4

pharmaceutical intermediate

Referencesame scaffold

(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide

CAS2223677-61-8

pharmaceutical raw material

Referencesame scaffold

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine

CAS179552-74-0

pharmaceutical intermediate

Referencesame scaffold

Erlotinib hydrochloride

CAS183319-69-9

pharmaceutical raw material

Identifiers
IUPAC Name

6-amino-4-(3-chloro-4-fluoroanilino)quinazolin-7-ol

InChIKey

YEFNIUDZICAGOU-UHFFFAOYSA-N

SMILES

C1=CC(=C(C=C1NC2=NC=NC3=CC(=C(C=C32)N)O)Cl)F

Synonyms (3)
  • Afatinib Impurity S

Sourcing 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-quinazolinol?

Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.

Post a Purchase Request→Supplier? List your product for this CAS→