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Home/Compounds/API/(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
C21H17ClF2N4O2
430.8 g/mol
API

(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

CAS1698024-73-5
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

ARS-1620 is a quinazoline derivative that functions as a potent, selective, and orally bioavailable covalent inhibitor of the KRAS G12C mutant protein. It is used in research and pharmaceutical manufacturing as a targeted compound for studying KRAS G12C-driven malignancies.

research compound for KRAS G12C mutant tumor studiespharmaceutical raw material for targeted inhibitor development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

CAS1698055-85-4

pharmaceutical raw material

StrongSame Parent

(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

CAS1698055-86-5

pharmaceutical raw material

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pharmaceutical raw material

Identifiers
IUPAC Name

1-[4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl]prop-2-en-1-one

InChIKey

ZRPZPNYZFSJUPA-UHFFFAOYSA-N

SMILES

C=CC(=O)N1CCN(CC1)C2=NC=NC3=C(C(=C(C=C32)Cl)C4=C(C=CC=C4F)O)F

Synonyms (11)
  • ARS-1323?
  • ARS-1620?
  • ARS-1630?
  • example 227