Mc-Val-Cit-PAB-Cl is a chemical compound used as a linker intermediate in the manufacturing of antibody-drug conjugates. Its structure includes a maleimide group for conjugation, a valine-citrulline dipeptide, and a chloromethyl-bearing aniline unit.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1639351-92-0
N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
pharmaceutical intermediate
2-((2,2-Diphenylvinyl)oxy)-4,6-dimethylpyrimidine
pharmaceutical intermediate
MC-Val-Ala-PAB-PNP
pharmaceutical intermediate
2,3,3-Trimethylindolenine
pharmaceutical intermediate
Ethyl 4-acetoxy-1-benzyl-2-methyl-1H-benzo[d]imidazole-6-carboxylate
pharmaceutical intermediate
Mc-Val-Ala-PAB
pharmaceutical intermediate
N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(chloromethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-6-(2,5-dioxopyrrol-1-yl)hexanamide
TUMQZNBKSWFFAZ-OFVILXPXSA-N
CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CCl)NC(=O)CCCCCN2C(=O)C=CC2=O