MC-Val-Ala-PAB-PNP is a chemical compound used as a linker reagent in the manufacturing of antibody-drug conjugates (ADCs). It contains a maleimide group for cysteine conjugation, a valine-alanine dipeptide cleavable by cathepsin B, and a p-nitrophenyl carbonate group for drug attachment.
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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MC-Val-Cit-PAB-PNP
research compound
2,3,3-Trimethylindolenine
pharmaceutical intermediate
Ethyl 4-acetoxy-1-benzyl-2-methyl-1H-benzo[d]imidazole-6-carboxylate
pharmaceutical intermediate
Decane-d22
pharmaceutical intermediate
4-(Chloromethyl)benzoic acid
pharmaceutical intermediate
[4-[[(2S)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]propanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate
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C[C@@H](C(=O)NC1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)[C@H](C(C)C)NC(=O)CCCCCN3C(=O)C=CC3=O
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