C26H23N7O2
465.5 g/mol
APIWarning
Acalabrutinib
CAS1420477-60-6EC814-272-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Acalabrutinib is a second-generation irreversible inhibitor of Bruton's tyrosine kinase (BTK), belonging to the imidazopyrazine class. It is an active pharmaceutical ingredient used in the manufacturing of products for oncology research and development.
Bruton's tyrosine kinase inhibitor for pharmaceutical manufacturingAntineoplastic agent research compoundApoptosis inducer in laboratory studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 1420477-60-6
Related Compounds
StrongSame Parent
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StrongSame Parent
Calquence
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ApplicationSame Use
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Referencestereoisomer of
Acalabrutinib enantiomer
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pharmaceutical raw material
Safety Reference
Warning
H373May cause damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
InChIKey
WDENQIQQYWYTPO-IBGZPJMESA-N
SMILES
CC#CC(=O)N1CCC[C@H]1C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5
Synonyms (18)
- Acalabrutinib (JAN/USAN/INN)
- ACP-196;Acalabrutinib
- Acalabrutinib
- Acalabrutinib (ACP-196)
- Acalabrutinib (Standard)
- Calquence
- Calquence (TN)
- Example 6
- acalabrutinibum