C22H21F4N5O3
479.4 g/mol
APIDanger
Pirtobrutinib
CAS2101700-15-4
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Pirtobrutinib is a pharmaceutical raw material and Bruton's tyrosine kinase (BTK) inhibitor used in the manufacturing of anti-cancer medications. It is an orally bioavailable compound that binds to and inhibits BTK, thereby suppressing B cell lymphocyte proliferation and survival.
pharmaceutical manufacturingresearch into BTK-mediated signaling pathways
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 2101700-15-4
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Safety Reference
Danger
H360May damage fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name
5-amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]pyrazole-4-carboxamide
InChIKey
FWZAWAUZXYCBKZ-NSHDSACASA-N
SMILES
C[C@@H](C(F)(F)F)N1C(=C(C(=N1)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC(=C3)F)OC)C(=O)N)N
Synonyms (17)
- LOXO-305
- MCL133
- RXC-005
- BTK Inhibitor LOXO-305
- BTK inhibitor 16
- LOXO-305;LY 3527727; RXC-005
- LY 3527727
- Pirtobrutinib
- Pirtobrutinib (LOXO-305)?
- WHO 11681
- pirtobrutinibum