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Home/Compounds/API/Osimertinib
C28H33N7O2
499.6 g/mol
APIDanger

Osimertinib

CAS1421373-65-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Osimertinib is a chemical compound used as an active pharmaceutical ingredient in pharmaceutical manufacturing. It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, primarily utilized in the preparation of drugs targeting specific non-small-cell lung carcinoma mutations.

pharmaceutical manufacturingresearch and development for targeted therapies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Osimertinib mesylate

CAS1421373-66-1

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.84

N-(2-((2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)(methyl)amino)ethyl)-3-((2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)amino)-N,N-dimethyl-3-oxopropan-1-aminium

CAS2564638-97-5

research compound

SimilarStructure SimilarSimilarity 0.80

Befotertinib

CAS1835667-63-4

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.79

N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-N-(3-((2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)amino)-3-oxopropyl)acrylamide

CAS2919324-18-6

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.72

Mobocertinib

CAS1847461-43-1

pharmaceutical raw material

ReferenceSame Category

Eglumine

CAS14216-22-9

pharmaceutical raw material

ReferenceSame Category

Entecavir

CAS142217-69-4

pharmaceutical raw material

ReferenceSame Category

2-amino-1,9-dihydro-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylene cyclopentyl)-6H-purine-6-one

CAS142217-81-0

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H302Harmful if swallowed
H317May cause an allergic skin reaction
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Osimertinib (CAS 1421373-65-0) is 2933.59.

HS code (international, 6-digit)

2933.59

EU CN code (8-digit)

2933 59 95

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide

InChIKey

DUYJMQONPNNFPI-UHFFFAOYSA-N

SMILES

CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC

Synonyms (15)
  • mereletinib (obsolete INN)
  • AZD 9291(Osimertinib)
  • AZD-9291 FREE BASE
  • Mereletinib
  • Osimertinib (AZD9291)
  • Osimertinib (Standard)
  • osimertinib
  • osimertinibum

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