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Home/Compounds/API/Sildenafil
C22H30N6O4S
474.6 g/mol
APIWarning

Sildenafil

CAS139755-83-2
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Sildenafil is a compound that acts as a phosphodiesterase 5 (PDE5) inhibitor and vasodilator agent. It is used as an active pharmaceutical ingredient (API) in the manufacturing of medications for urological applications.

Phosphodiesterase 5 inhibitorsUrological agentsVasodilator agents

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Sildenafil citrate

CAS171599-83-0

pharmaceutical raw material

StrongStructure SimilarSimilarity 0.86

Desmethylsildenafil

CAS139755-82-1

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.84

Sildenafil N-oxide

CAS1094598-75-0

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.82

Isobutyl sildenafil

CAS1391053-95-4

pharmaceutical raw material

ReferenceSame Category

4-(2-ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide

CAS139756-03-9

pharmaceutical raw material

ReferenceSame Category

Uk-088800

CAS139756-21-1

pharmaceutical raw material

ReferenceSame Category

5-(5-chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo(4,3-D)pyrimidin-7-one

CAS139756-22-2

pharmaceutical raw material

ReferenceSame Category

Shr-1258 dimaleate

CAS1397922-61-0

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H319Causes serious eye irritation
H412Harmful to aquatic life with long lasting effects
H315Causes skin irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for Sildenafil (CAS 139755-83-2) is 2935.90.

HS code (international, 6-digit)

2935.90

EU CN code (8-digit)

2935 90 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one

InChIKey

BNRNXUUZRGQAQC-UHFFFAOYSA-N

SMILES

CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C

Synonyms (40)
  • Sildenafil (INN)
  • 1udt
  • 1xos
  • 2h42
  • Aphrodil
  • Aphrodil (TN)
  • Nipatra
  • Patrex
  • SILDENAFIL; VIAGRA
  • Sildenafil - Bio-X trade mark
  • Sildenafil Impurity J
  • Sildenafil actavis
  • Sildenafil ratiopharm
  • Sildenafil teva
  • Sildenafilo
  • UK 92480-10
  • Vizarsin
  • sildenafil
  • sildenafilum

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