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Home/Compounds/Pharmaceutical Intermediate/Sildenafil N-oxide
C22H30N6O5S
490.6 g/mol
Pharmaceutical IntermediateWarning

Sildenafil N-Oxide

CAS1094598-75-0
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

Sildenafil N-Oxide is a pharmaceutical impurity reference standard used primarily in quality control and analytical testing for sildenafil-containing products. It is a structural analog of sildenafil, featuring an N-oxide functional group, and is supplied for research and manufacturing applications.

pharmaceutical impurity reference standardquality control testinganalytical method development

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.84

Sildenafil

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SimilarStructure SimilarSimilarity 0.83

Desmethylsildenafil

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SimilarStructure SimilarSimilarity 0.75

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Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Warning
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H412Harmful to aquatic life with long lasting effects
Identifiers
IUPAC Name

5-[2-ethoxy-5-(4-methyl-4-oxidopiperazin-4-ium-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one

InChIKey

JQGFLCMKCZPSEC-UHFFFAOYSA-N

SMILES

CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CC[N+](CC4)(C)[O-])OCC)C

Synonyms (17)
  • SILDENAFIL CITRATE IMPURITY B (EP IMPURITY)
  • Sildenafil Citrate Imp. B (EP); Sildenafil Imp. B (EP); 5-[2-Ethoxy-5-[(4-methyl-4-oxidopiperazin-1-yl)sulfonyl]phenyl]-1-methyl-3-propyl-6,7-dihydro-1Hpyrazolo[4,3-d]pyrimidin-7-one; Sildenafil N-Oxide; Sildenafil Citrate Impurity B; Sildenafil Impurity B
  • Sildenafil EP Impurity B
  • Sildenafil N-Oxide
  • Sildenafil citrate impurity B

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