C23H27NO5
397.5 g/mol
Pharmaceutical IntermediateWarning
(2R,3S)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS138797-71-4EC882-206-8
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
This compound is a protected derivative of D-threonine, featuring a fluorenylmethoxycarbonyl (Fmoc) group and a tert-butyl ether protecting group. It is commonly used as a building block in solid-phase peptide synthesis, enabling the incorporation of D-threonine residues with protected side chains.
Building block for peptide synthesisIntermediate in pharmaceutical manufacturing
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 138797-71-4
Related Compounds
SimilarStructure SimilarSimilarity 0.77
(2S,3R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methoxybutanoic acid
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects
Identifiers
IUPAC Name
(2R,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]butanoic acid
InChIKey
LZOLWEQBVPVDPR-VBKZILBWSA-N
SMILES
C[C@@H]([C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OC(C)(C)C
Synonyms (18)
- Fmoc-D-Thr(tBu)-OH
- Fmoc-O-tert-butyl-D-threonine
- US20250388584, Example 142