C21H23NO4
353.4 g/mol
Pharmaceutical IntermediateWarning
(2R)-2-{[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO}-4-METHYLPENTANOIC ACID
CAS114360-54-2EC871-840-0
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
This compound is a leucine derivative featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group and D-configuration stereochemistry. It serves as a building block in peptide synthesis, enabling the incorporation of D-leucine residues into peptide chains during solid-phase or solution-phase assembly.
Peptide synthesis building blockLaboratory reagent for solid-phase peptide synthesis (SPPS)
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 114360-54-2
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SimilarStructure SimilarSimilarity 0.73
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
InChIKey
CBPJQFCAFFNICX-LJQANCHMSA-N
SMILES
CC(C)C[C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms (15)
- (r)-n-fmoc-leucine
- Fmoc-D-Leu-OH
- Fmoc-D-Leu-OH, >=95.0% (TLC)
- Fmoc-D-leucine
- Fmoc-DLeu
- N-Fmoc-D-leucine
- Npc 15199