C22H25NO5
383.4 g/mol
Pharmaceutical IntermediateWarning
9-fluorenylmethyloxycarbonyl-D-Ser(t-butyl)-OH
CAS128107-47-1EC810-913-3
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
This compound is a protected D-serine derivative used as a building block in solid-phase peptide synthesis. The Fmoc group protects the amine, while the tert-butyl group protects the side-chain hydroxyl, enabling selective deprotection during chain assembly.
building block for peptide synthesisprotected amino acid for solid-phase peptide synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.77
Fmoc-Ser(tBu)-Gly-OH
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SimilarStructure SimilarSimilarity 0.75
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SimilarStructure SimilarSimilarity 0.73
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Fmoc-D-leucine
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ReferenceSame Category
3-Hydroxyazetidine-1-carboxylic acid benzyl ester
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Related Reading
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoic acid
InChIKey
REITVGIIZHFVGU-LJQANCHMSA-N
SMILES
CC(C)(C)OC[C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms (15)
- Fmoc-D-Ser(Bu-t)-OH
- Fmoc-D-Ser(tBu)-OH
- Fmoc-O-tert-butyl-D-serine
- N-Fmoc-O-tert-butyl-D-Serine
- O-tert-Butyl-N-Fmoc-L-serine
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