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Home/Compounds/API/Cobimetinib fumarate
C46H46F6I2N6O8
1178.7 g/mol
API

Cobimetinib Fumarate

CAS1369665-02-0
Category
API
Compound Class
Other
Primary Use
Pharmaceutical Raw Material

Cobimetinib fumarate is a fumarate salt of cobimetinib, formulated by combining two molecules of cobimetinib with one molecule of fumaric acid. It functions as an inhibitor of mitogen-activated protein kinase (MEK) and is utilized as an antineoplastic agent in combination therapy for certain cancers.

pharmaceutical raw material for MEK inhibitor manufacturingactive pharmaceutical ingredient (API) for cancer research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Identifiers
IUPAC Name

(E)-but-2-enedioic acid;bis([3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone)

InChIKey

RESIMIUSNACMNW-BXRWSSRYSA-N

SMILES

C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O.C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O.C(=C/C(=O)O)\C(=O)O

Synonyms (12)
  • Cobimetinib fumarate (USAN)
  • Cobimetinib Fumarate
  • Cobimetinib fumarate - Bio-X
  • Cobimetinib hemifumarate
  • Cotellic (TN)
  • GDC-0973 hemifumarate
  • Xl-518 hemifumarate