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Home/Compounds/API/Lotilaner
C20H14Cl3F6N3O3S
596.8 g/mol
APIWarning

Lotilaner

CAS1369852-71-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Lotilaner is an isoxazoline compound that acts as a selective inhibitor of GABA-gated chloride channels in mites. It is used as an ectoparasiticide for companion animals, particularly in veterinary pharmaceutical manufacturing.

Ectoparasiticide for companion animalsPharmaceutical raw material for veterinary products

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

Lidocaine

CAS137-58-6

pharmaceutical raw material

ReferenceSame Category

Amprolium chloride hydrochloride

CAS137-88-2

pharmaceutical raw material

ReferenceSame Category

Elbasvir

CAS1370468-36-2

pharmaceutical raw material

ReferenceSame Category

Pimecrolimus

CAS137071-32-0

active pharmaceutical ingredient

Safety Reference

Environmental Hazard
Environmental Hazard
Warning
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for Lotilaner (CAS 1369852-71-0) is 2934.99.

HS code (international, 6-digit)

2934.99

EU CN code (8-digit)

2934 99 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

3-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]thiophene-2-carboxamide

InChIKey

HDKWFBCPLKNOCK-SFHVURJKSA-N

SMILES

CC1=C(SC(=C1)C2=NO[C@@](C2)(C3=CC(=C(C(=C3)Cl)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F

Synonyms (18)
  • XDEMVY
  • Lotilaner (USAN/INN)
  • Credelio
  • Credelio CAT
  • Lotilaner
  • Lotilaner ophthalmic solution
  • TP 03
  • Xdemvy (TN)
  • lotilanerum

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