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Home/Compounds/API/Lotilaner
C20H14Cl3F6N3O3S
596.8 g/mol
APIWarning

Lotilaner

CAS1369852-71-0
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Lotilaner is an isoxazoline compound that acts as a selective inhibitor of GABA-gated chloride channels in mites. It is used as an ectoparasiticide for companion animals, particularly in veterinary pharmaceutical manufacturing.

Ectoparasiticide for companion animalsPharmaceutical raw material for veterinary products

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

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CAS137-58-6

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ReferenceSame Category

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ReferenceSame Category

Pimecrolimus

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active pharmaceutical ingredient

Safety Reference

Environmental Hazard
Environmental Hazard
Warning
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
Identifiers
IUPAC Name

3-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]thiophene-2-carboxamide

InChIKey

HDKWFBCPLKNOCK-SFHVURJKSA-N

SMILES

CC1=C(SC(=C1)C2=NO[C@@](C2)(C3=CC(=C(C(=C3)Cl)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F

Synonyms (18)
  • XDEMVY
  • Lotilaner (USAN/INN)
  • Credelio
  • Credelio CAT
  • Lotilaner
  • Lotilaner ophthalmic solution
  • TP 03
  • Xdemvy (TN)
  • lotilanerum