C23H23N3O5
421.4 g/mol
APIDanger
Topotecan
CAS123948-87-8
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Topotecan is a pyranoindolizinoquinoline compound used as an antineoplastic agent. It is a derivative of camptothecin and functions by binding to the topoisomerase I-DNA complex, preventing the religation of single-strand breaks.
antineoplastic agenttopoisomerase I inhibitor
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Topotecan hydrochloride
CAS119413-54-6
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.79
Chimmitecan
CAS185425-25-6
pharmaceutical raw material
ReferenceSame Category
Ixazomib citrate
CAS1239908-20-3
pharmaceutical raw material
ReferenceSame Category
Mecetronium bromide
CAS124-03-8
pharmaceutical raw material
ReferenceSame Category
Triamcinolone
CAS124-94-7
pharmaceutical raw material
ReferenceSame Category
AGN-PC-07RIXJ
CAS1240470-84-1
pharmaceutical raw material
Referencesame scaffold
10-hydroxycamptothecin
CAS19685-09-7
pharmaceutical raw material
Referencesame scaffold
9-aminocamptothecin
CAS91421-43-1
pharmaceutical raw material
Safety Reference
Danger
H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H341Suspected of causing genetic defects
Customs Tariff Classification
The international HS code for Topotecan (CAS 123948-87-8) is 2939.79.
HS code (international, 6-digit)
2939.79
EU CN code (8-digit)
2939 79 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
InChIKey
UCFGDBYHRUNTLO-QHCPKHFHSA-N
SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O
Synonyms (39)
- Topotecane [INN-French]
- Topotecanum [INN-Latin]
- (S)-Topotecan
- Hycamptamine
- Hycamptin
- Hycamtamine
- Hycamtin (TN)
- Nogitecan
- SK&F 104864 A
- SK&F-104864
- SK&F-S-104864A
- SKF-S 104864
- TopoCED
- Topophore C
- Topotecan (BAN)
- Topotecan lactone
- Topotecane
- Topotecanum
- topotecan
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Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.