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Home/Compounds/API/10-hydroxycamptothecin
C20H16N2O5
364.4 g/mol
APIWarning

10-Hydroxycamptothecin

CAS19685-09-7EC613-598-9
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material

10-Hydroxycamptothecin is a pyranoindolizinoquinoline compound under investigation in clinical research. It is a naturally occurring alkaloid found in Nothapodytes nimmoniana, Fusarium solani, and Camptotheca acuminata.

pharmaceutical research compoundactive pharmaceutical ingredient

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.80

Camptothecin

CAS7689-03-4

pharmaceutical raw material

ReferenceSame Category

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CAS19716-79-1

pharmaceutical raw material

ReferenceSame Category

Tolebrutinib

CAS1971920-73-6

pharmaceutical raw material

ReferenceSame Category

Dynastat

CAS197502-82-2

pharmaceutical raw material

ReferenceSame Category

Tigecycline hydrochloride

CAS197654-04-9

pharmaceutical raw material

Referencesame scaffold

7-ethyl-10-hydroxycamptothecin

CAS86639-52-3

pharmaceutical raw material

Referencesame scaffold

9-aminocamptothecin

CAS91421-43-1

pharmaceutical raw material

Referencesame scaffold

Topotecan hydrochloride

CAS119413-54-6

pharmaceutical raw material

Safety Reference

Toxic
Toxic
Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H340May cause genetic defects
H350May cause cancer
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name

(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione

InChIKey

HAWSQZCWOQZXHI-FQEVSTJZSA-N

SMILES

CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O

Synonyms (22)
  • 10-HCPT
  • Irinotecan EP Impurity B; Camptothecin 10-Hydroxy Impurity
  • (S)-10-Hydroxycamptothecin
  • 10-Hydroxy-CPT
  • 10-Hydroxycamp-totecin
  • 10-Hydroxycamptothecin
  • 10-hydroxycamptothecine
  • Camptothecin, 10-hydroxy-
  • Camptothecin, hydroxy-
  • Camptothecine, 10-hydroxy-
  • Hydroxycamptothecin
  • Hydroxycamptothecine
  • ethyl(dihydroxy)[?]dione

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