C20H16N2O5
364.4 g/mol
APIWarning
10-Hydroxycamptothecin
CAS19685-09-7EC613-598-9
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material
10-Hydroxycamptothecin is a pyranoindolizinoquinoline compound under investigation in clinical research. It is a naturally occurring alkaloid found in Nothapodytes nimmoniana, Fusarium solani, and Camptotheca acuminata.
pharmaceutical research compoundactive pharmaceutical ingredient
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 19685-09-7
Related Compounds
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Referencesame scaffold
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H340May cause genetic defects
H350May cause cancer
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life
Identifiers
IUPAC Name
(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
InChIKey
HAWSQZCWOQZXHI-FQEVSTJZSA-N
SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O
Synonyms (22)
- 10-HCPT
- Irinotecan EP Impurity B; Camptothecin 10-Hydroxy Impurity
- (S)-10-Hydroxycamptothecin
- 10-Hydroxy-CPT
- 10-Hydroxycamp-totecin
- 10-Hydroxycamptothecin
- 10-hydroxycamptothecine
- Camptothecin, 10-hydroxy-
- Camptothecin, hydroxy-
- Camptothecine, 10-hydroxy-
- Hydroxycamptothecin
- Hydroxycamptothecine
- ethyl(dihydroxy)[?]dione