C23H24ClN3O5
457.9 g/mol
APIDanger
TOPOTECAN HYDROCHLORIDE
CAS119413-54-6
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Topotecan hydrochloride is a synthetic, water-soluble analog of camptothecin and functions as a topoisomerase inhibitor. It is used as an active pharmaceutical ingredient in the manufacturing of chemotherapeutic medications.
Active pharmaceutical ingredient for cancer treatment formulations
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
StrongSame Parent
Topotecan
CAS123948-87-8
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.79
Chimmitecan
CAS185425-25-6
pharmaceutical raw material
ReferenceSame Category
PUBCHEM_16133823
CAS119418-04-1
pharmaceutical raw material
ReferenceSame Category
Fruquintinib
CAS1194506-26-7
pharmaceutical raw material
ReferenceSame Category
Danofloxacin mesylate
CAS119478-55-6
pharmaceutical raw material
ReferenceSame Category
Meropenem trihydrate
CAS119478-56-7
pharmaceutical raw material
Referencesame scaffold
10-hydroxycamptothecin
CAS19685-09-7
pharmaceutical raw material
Referencesame scaffold
9-aminocamptothecin
CAS91421-43-1
pharmaceutical raw material
Safety Reference
Danger
H300Fatal if swallowed
H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs
H412Harmful to aquatic life with long lasting effects
Customs Tariff Classification
The international HS code for TOPOTECAN HYDROCHLORIDE (CAS 119413-54-6) is 2939.79.
HS code (international, 6-digit)
2939.79
EU CN code (8-digit)
2939 79 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
InChIKey
DGHHQBMTXTWTJV-BQAIUKQQSA-N
SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl
Synonyms (36)
- Topotecan hydrochloride (USAN)
- Evotopin
- Evotropin
- Hycamptamine hydrochloride
- Hycamtin
- Hycamtin (TN)
- Hycamtin (TN) (GlaxoSmith)
- Hydrochloride, Nogitecan
- Hydrochloride, Topotecan
- Nogitecan hydrochloride
- Nogitecan hydrochloride (JAN)
- Potactasol (TN)
- SK&F S-104864-A
- SKF 104864A
- SKF 104864A; NSC 609669
- TOPOTECAN HYDROCHLORIDE
- Topotecan (as hydrochloride)
- Topotecan Actavis
- Topotecan Hcl
- Topotecan Hospira
- Topotecan Hydrocholoride
- Topotecan monohydrochloride
- Topotecan teva
- potactasol
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