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Home/Compounds/API/Abemaciclib mesylate
C28H36F2N8O3S
602.7 g/mol
API

Abemaciclib mesylate

CAS1231930-82-7
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

Abemaciclib mesylate is a salt form of abemaciclib, an orally available cyclin-dependent kinase (CDK) inhibitor that targets CDK4 and CDK6, with potential antineoplastic activity. It inhibits retinoblastoma protein phosphorylation, thereby arresting the cell cycle in the G1 phase and suppressing cancer cell growth.

active pharmaceutical ingredient for pharmaceutical manufacturingresearch compound for cell cycle regulation studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Abemaciclib

CAS1231929-97-7

pharmaceutical raw material

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5-trans-25-hydroxycholecalciferol

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PUBCHEM_44134997

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pharmaceutical raw material

Identifiers
IUPAC Name

N-[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridinyl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine;methanesulfonic acid

InChIKey

NCJPFQPEVDHJAZ-UHFFFAOYSA-N

SMILES

CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O

Synonyms (14)
  • ABEMACICLIB MESILATE
  • Abemaciclib (ly2835219)
  • Abemaciclib mesylate
  • Abemaciclib methanesulfonate
  • LY-2835219 methanesulfonate
  • LY2835219 Mesylate
  • LY2835219(Abemaciclib)

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