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Home/Compounds/API/Clofarabine
C10H11ClFN5O3
303.68 g/mol
APIDanger

Clofarabine

CAS123318-82-1
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Clofarabine is a nucleoside metabolic inhibitor used as an antineoplastic antimetabolite. It functions by inhibiting nucleic acid synthesis, making it a compound of interest in pharmaceutical manufacturing for cancer research.

Pharmaceutical raw material for antineoplastic researchNucleic acid synthesis inhibitor in laboratory studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Toxic
Toxic
Health Hazard
Health Hazard
Danger
H300Fatal if swallowed
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name

(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

InChIKey

WDDPHFBMKLOVOX-AYQXTPAHSA-N

SMILES

C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N

Synonyms (34)
  • CFB
  • Clofarabine (JAN/USAN/INN)
  • 2-Cl-2'-F-araA
  • C1-F-Ara-A
  • CAFdA
  • CLOFARABINE [MART.]
  • Cl-F-Ara-A
  • Clofarabine
  • Clofarabine, >=98% (HPLC)
  • Clofarabine,Clolar, Evoltra
  • Clofarex
  • Clolar
  • Clolar (TN)
  • Evoltra
  • clofarabina
  • clofarabinum