C27H32N8O2
500.6 g/mol
APIDanger
Adavosertib
CAS955365-80-7
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material
Adavosertib is a small molecule inhibitor of the kinase enzyme WEE1, under investigation as an experimental anti-cancer drug candidate. It is a compound used in pharmaceutical research and development.
research compound for WEE1 kinase inhibition studiespharmaceutical raw material for laboratory-scale synthesis
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 955365-80-7
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Safety Reference
Danger
H302Harmful if swallowed
H340May cause genetic defects
H372Causes damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name
1-[6-(2-hydroxypropan-2-yl)-2-pyridinyl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
InChIKey
BKWJAKQVGHWELA-UHFFFAOYSA-N
SMILES
CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
Synonyms (27)
- 8X7
- EX-A331
- Adavosertib (USAN)
- AZD 1775
- Adavosertib
- Adavosertib (Standard)
- Adavosertib; MK-1775
- Adavosertib; MK-1775; MK 1775
- MK 1775
- MK-1775 (AZD-1775)
- MK-1775 (WEE-1)
- MK-1775(AZD-1775,Adavosertib)
- adavosertibum