C21H15F4N5O2S
477.4 g/mol
APIDanger
Apalutamide
CAS956104-40-8
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Apalutamide is a nonsteroidal androgen receptor antagonist used as a pharmaceutical raw material for the manufacturing of medications indicated in castration-resistant prostate cancer. It selectively binds to the androgen receptor ligand-binding domain, blocking nuclear translocation and transcription of androgen receptor gene targets.
pharmaceutical manufacturing for non-metastatic castration-resistant prostate cancer therapyresearch compound for androgen receptor signaling studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
Sourcing Apalutamide?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.
Related Compounds
StrongStructure SimilarSimilarity 0.88
Apalutamide Dithio Impurity
CAS2649802-40-2
pharmaceutical raw material
StrongStructure SimilarSimilarity 0.86
Apalutamide Di-(2-fluoro-N-methylbenzamide)
CAS2894796-76-8
pharmaceutical raw material
StrongStructure SimilarSimilarity 0.86
Apalutamide metabolite M2
CAS1332391-92-0
pharmaceutical raw material
SimilarStructure SimilarSimilarity 0.84
Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
CAS1950587-19-5
research compound
ReferenceSame Category
Ranolazine
CAS95635-55-5
pharmaceutical raw material
ReferenceSame Category
Ranolazine hydrochloride
CAS95635-56-6
pharmaceutical raw material
ReferenceSame Category
Fluindione
CAS957-56-2
pharmaceutical raw material
ReferenceSame Category
(7a,17a)-17-Hydroxy-3-oxo-pregna-4,9(11)-diene-7,21-dicarboxylicacid g-lactone methyl ester
CAS95716-70-4
pharmaceutical raw material
Safety Reference
Danger
H360May damage fertility or the unborn child
Customs Tariff Classification
The international HS code for Apalutamide (CAS 956104-40-8) is 2933.39, 3824.99.
HS code (international, 6-digit)
2933.39, 3824.99
EU CN code (8-digit)
2933 39 99, 3824 99 92
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide
InChIKey
HJBWBFZLDZWPHF-UHFFFAOYSA-N
SMILES
CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F
Synonyms (15)
- Apalutamide (JAN/INN)
- 956104-40-8 (free base)
- Apalutamide (ARN-509)
- Apalutamide (Standard)
- Erleada
- Erleada (TN)
- apalutamida
- apalutamide
- apalutamidum
Sourcing Apalutamide?
Post a free purchase request — no account needed. It reaches suppliers of this product, and replies go straight to your inbox.