C21H15F4N5O2S
477.4 g/mol
APIDanger
Apalutamide
CAS956104-40-8
Category
API
Compound Class
Amide
Primary Use
Pharmaceutical Raw Material
Apalutamide is a nonsteroidal androgen receptor antagonist used as a pharmaceutical raw material for the manufacturing of medications indicated in castration-resistant prostate cancer. It selectively binds to the androgen receptor ligand-binding domain, blocking nuclear translocation and transcription of androgen receptor gene targets.
pharmaceutical manufacturing for non-metastatic castration-resistant prostate cancer therapyresearch compound for androgen receptor signaling studies
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 956104-40-8
Related Compounds
StrongStructure SimilarSimilarity 0.88
Apalutamide Dithio Impurity
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StrongStructure SimilarSimilarity 0.86
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SimilarStructure SimilarSimilarity 0.84
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Safety Reference
Danger
H360May damage fertility or the unborn child
Identifiers
IUPAC Name
4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide
InChIKey
HJBWBFZLDZWPHF-UHFFFAOYSA-N
SMILES
CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F
Synonyms (15)
- Apalutamide (JAN/INN)
- 956104-40-8 (free base)
- Apalutamide (ARN-509)
- Apalutamide (Standard)
- Erleada
- Erleada (TN)
- apalutamida
- apalutamide
- apalutamidum