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Home/Compounds/API/Blz-945
C20H22N4O3S
398.5 g/mol
API

BLZ945

CAS953769-46-5
Category
API
Compound Class
Heterocycle
Primary Use
Pharmaceutical Raw Material

Sotuletinib (BLZ945) is an orally bioavailable inhibitor of colony-stimulating factor 1 receptor (CSF-1R). It selectively binds to CSF-1R on tumor-associated macrophages, blocking receptor activity and modulating immune signaling in the tumor microenvironment.

Research compound for CSF-1R inhibition studiesBiochemical tool for macrophage biology research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

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CAS95382-33-5

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Adavosertib

CAS955365-80-7

pharmaceutical raw material

ReferenceSame Category

4-Hydroxy-2,2-diphenylbutyric acid gamma-lactone

CAS956-89-8

pharmaceutical raw material

Customs Tariff Classification

The international HS code for BLZ945 (CAS 953769-46-5) is 2934.20.

HS code (international, 6-digit)

2934.20

EU CN code (8-digit)

2934 20 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-1,3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide

InChIKey

ADZBMFGQQWPHMJ-RHSMWYFYSA-N

SMILES

CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)N[C@@H]4CCCC[C@H]4O

Synonyms (13)
  • BLZ945
  • EX-A817
  • P-BLZ945
  • CSF-1R INHIBITOR BLZ945
  • KVA-E-23A
  • sotuletinib

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