Home/Compounds/Pharmaceutical Intermediate/(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate
C20H17FO6
372.3 g/mol
Pharmaceutical IntermediateWarning
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
CAS874638-80-9EC618-021-4
Category
Pharmaceutical Intermediate
Compound Class
Ester
Primary Use
Pharmaceutical Intermediate
This compound is a chiral, fluorinated lactone functionalized with two benzoate ester groups. It is primarily used as an intermediate in the manufacturing of the antiviral pharmaceutical agent sofosbuvir.
Sofosbuvir intermediate
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 874638-80-9
Related Compounds
SimilarStructure SimilarSimilarity 0.79
(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamama-lactone 3,5-bis(4-chlorobenzoate)
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SimilarStructure SimilarSimilarity 0.78
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SimilarStructure SimilarSimilarity 0.73
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Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Identifiers
IUPAC Name
[(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxooxolan-2-yl]methyl benzoate
InChIKey
OUKYMZJNLWKCSO-JXXFODFXSA-N
SMILES
C[C@]1([C@@H]([C@H](OC1=O)COC(=O)C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)F
Synonyms (10)
- Sofosbuvir Impurity 46