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Home/Compounds/Pharmaceutical Intermediate/4,7-dichloroquinoline
C9H5Cl2N
198.05 g/mol
Pharmaceutical IntermediateWarning

4,7-Dichloroquinoline

CAS86-98-6EC201-714-7
Category
Pharmaceutical Intermediate
Compound Class
Heterocycle
Primary Use
Pharmaceutical Intermediate

4,7-Dichloroquinoline is a two-ring heterocyclic compound used as a chemical intermediate in the manufacture of aminoquinoline antimalarial drugs such as amodiaquine, chloroquine, and hydroxychloroquine.

chemical intermediate for amodiaquinechemical intermediate for chloroquinechemical intermediate for hydroxychloroquine

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

4,7-Dichloroquinoline

CAS1138471-54-1

pharmaceutical intermediate

ReferenceSame Category

Ethyl L-thiazolidine-4-carboxylate hydrochloride

CAS86028-91-3

pharmaceutical intermediate

ReferenceSame Category

4-CHLORO-5-FLUOROPYRIDINE-3-CARBOXYLIC ACID

CAS860296-20-4

pharmaceutical intermediate

ReferenceSame Category

Fmoc-S-acetamidomethyl-L-cysteine

CAS86060-81-3

pharmaceutical intermediate

ReferenceSame Category

N'-Fmoc-N-Cbz-L-Lysine

CAS86060-82-4

pharmaceutical intermediate

Referencestereoisomer of

4,7-Dichloroquinoline-15N

CAS366495-92-3

pharmaceutical intermediate

Safety Reference

Harmful
Harmful
Environmental Hazard
Environmental Hazard
Warning
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for 4,7-Dichloroquinoline (CAS 86-98-6) is 2933.49.

HS code (international, 6-digit)

2933.49

EU CN code (8-digit)

2933 49 10

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

4,7-dichloroquinoline

InChIKey

HXEWMTXDBOQQKO-UHFFFAOYSA-N

SMILES

C1=CC2=C(C=CN=C2C=C1Cl)Cl

Synonyms (11)
  • Hydroxychloroquine EP Impurity G
  • Hydroxychloroquine Sulfate EP Impurity G
  • 4,7-Dichloroquinoline
  • 4,7-dichloroquinolinium
  • 4,7-dichloroquinolne
  • DICHLOROQUINOLINE, 4,7-
  • QUINOLINE, 4,7-DICHLORO-
  • Quinoline,7-dichloro-

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