C21H22N2O5S
414.5 g/mol
Pharmaceutical IntermediateWarning
Fmoc-cys (acm)
CAS86060-81-3
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate
Fmoc-cys (acm) is a side-chain protected amino acid derivative used in solid-phase peptide synthesis. The Fmoc group protects the alpha-amino group while the acetamidomethyl (acm) group protects the thiol side chain of cysteine, enabling selective deprotection during peptide assembly.
side-chain protected amino acid for peptide synthesisbuilding block in solid-phase peptide synthesisresearch reagent for peptide chemistry
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.74
Fmoc-S-Methyl-L-Cysteine
CAS138021-87-1
research compound
ReferenceSame Category
N'-Fmoc-N-Cbz-L-Lysine
CAS86060-82-4
pharmaceutical intermediate
ReferenceSame Category
(S)-(+)-3-Hydroxytetrahydrofuran
CAS86087-23-2
pharmaceutical intermediate
ReferenceSame Category
(R)-2-Amino-3-methoxypropanoic acid hydrochloride
CAS86118-10-7
pharmaceutical intermediate
ReferenceSame Category
Boc-O-Methyl-D-serine
CAS86123-95-7
pharmaceutical intermediate
Related Reading
Safety Reference
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for Fmoc-cys (acm) (CAS 86060-81-3) is 2930.90.
HS code (international, 6-digit)
2930.90
EU CN code (8-digit)
2930 90 16
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(2R)-3-(acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
InChIKey
CSMYOORPUGPKAP-IBGZPJMESA-N
SMILES
CC(=O)NCSC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms (20)
- Fmoc-Cys(Acm)-OH
- Fmoc-S-acetamidomethyl-cys
- Fmoc-cys (acm)
- fmoc-l-cys(acm)-oh
- fmoc-l-cysteine(acm)
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