C17H20N2
252.35 g/mol
Pharmaceutical IntermediateWarning
1-Benzhydrylpiperazine
CAS841-77-0EC212-667-7
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
1-Benzhydrylpiperazine (diphenylmethylpiperazine) is a piperazine derivative featuring a benzhydryl group attached to one of the nitrogen atoms of the piperazine ring. It serves as a pharmaceutical intermediate used in the manufacture of antihistamine compounds such as cyclizine and cinnarizine.
pharmaceutical intermediate for antihistaminesprecursor for cyclizineprecursor for cinnarizine
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 841-77-0
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Referencesame scaffold
4,4'-Difluorobenzhydrylpiperazine
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Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Identifiers
IUPAC Name
1-benzhydrylpiperazine
InChIKey
NWVNXDKZIQLBNM-UHFFFAOYSA-N
SMILES
C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=CC=C3
Synonyms (22)
- 1-(Diphenylmethyl)piperazine; Cinnarizine Imp. A (EP); Cinnarizine Impurity A
- Cinnarizine EP Impurity A
- 1-(Diphenylmethyl)piperazine
- 1-Benzhydrylpiperazine
- 1-benzhydrylpiperazin
- 1-benzyhydrylpiperazine
- 4-Benzhydrylpiperazine
- 4-diphenylmethylpiperazine
- Benzhydrylpiperazine
- CINNARIZINE IMPURITY A
- Cinnarizine metabolite M1
- Diphenylmethylpiperazine
- N-(Diphenylmethyl)piperazine
- N-Benzhydrylpiperazine
- Norcyclizine
- Normethylcyclizine
- benzhydrylpiperazin
- diphenylmethylpiperazin
- mono-benzhydrylpiperazine