C17H20N2
252.35 g/mol
Pharmaceutical IntermediateWarning
1-Benzhydrylpiperazine
CAS841-77-0EC212-667-7
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate
1-Benzhydrylpiperazine (diphenylmethylpiperazine) is a piperazine derivative featuring a benzhydryl group attached to one of the nitrogen atoms of the piperazine ring. It serves as a pharmaceutical intermediate used in the manufacture of antihistamine compounds such as cyclizine and cinnarizine.
pharmaceutical intermediate for antihistaminesprecursor for cyclizineprecursor for cinnarizine
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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Related Compounds
SimilarStructure SimilarSimilarity 0.79
1-(4-Chlorobenzhydryl)piperazine
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SimilarStructure SimilarSimilarity 0.79
(-)-norchlorcyclizine
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pharmaceutical intermediate
SimilarStructure SimilarSimilarity 0.79
Norchlorcyclizine
CAS303-26-4
pharmaceutical intermediate
ReferenceSame Category
5-Chloro-2-methyl-1-phenyl-1H-benzimidazole
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pharmaceutical intermediate
ReferenceSame Category
2-Methylpropaneboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester
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ReferenceSame Category
Isobutaneboronic acid
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pharmaceutical intermediate
ReferenceSame Category
TERT-BUTYL 3-HYDROXY-4,4-DIMETHOXYPIPERIDINE-1-CARBOXYLATE
CAS841286-80-4
pharmaceutical intermediate
Referencesame scaffold
4,4'-Difluorobenzhydrylpiperazine
CAS27469-60-9
research compound
Safety Reference
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
Customs Tariff Classification
The international HS code for 1-Benzhydrylpiperazine (CAS 841-77-0) is 2933.59.
HS code (international, 6-digit)
2933.59
EU CN code (8-digit)
2933 59 95
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
1-benzhydrylpiperazine
InChIKey
NWVNXDKZIQLBNM-UHFFFAOYSA-N
SMILES
C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=CC=C3
Synonyms (22)
- 1-(Diphenylmethyl)piperazine; Cinnarizine Imp. A (EP); Cinnarizine Impurity A
- Cinnarizine EP Impurity A
- 1-(Diphenylmethyl)piperazine
- 1-Benzhydrylpiperazine
- 1-benzhydrylpiperazin
- 1-benzyhydrylpiperazine
- 4-Benzhydrylpiperazine
- 4-diphenylmethylpiperazine
- Benzhydrylpiperazine
- CINNARIZINE IMPURITY A
- Cinnarizine metabolite M1
- Diphenylmethylpiperazine
- N-(Diphenylmethyl)piperazine
- N-Benzhydrylpiperazine
- Norcyclizine
- Normethylcyclizine
- benzhydrylpiperazin
- diphenylmethylpiperazin
- mono-benzhydrylpiperazine
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