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Home/Compounds/Pharmaceutical Intermediate/1-(4-Chlorobenzhydryl)piperazine
C17H19ClN2
286.8 g/mol
Pharmaceutical IntermediateWarning

1-(4-Chlorobenzhydryl)piperazine

CAS130018-88-1EC206-137-4
Category
Pharmaceutical Intermediate
Compound Class
Amine
Primary Use
Pharmaceutical Intermediate

1-(4-Chlorobenzhydryl)piperazine is a chemical compound used as a pharmaceutical intermediate in manufacturing processes. It features a piperazine ring substituted with a chlorinated diphenylmethyl group, contributing to its role in the synthesis of active pharmaceutical ingredients.

pharmaceutical intermediate

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

Norchlorcyclizine

CAS303-26-4

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.79

Diphenylmethylpiperazine

CAS841-77-0

pharmaceutical intermediate

ReferenceSame Category

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS130049-82-0

pharmaceutical intermediate

ReferenceSame Category

[2-(Difluoromethoxy)pyridin-3-yl]boronic acid

CAS1300750-50-8

pharmaceutical intermediate

ReferenceSame Category

N,N-didesmethylvenlafaxine hydrochloride

CAS130198-05-9

pharmaceutical intermediate

ReferenceSame Category

(+)-tert-butyl glycidyl ether

CAS130232-97-2

pharmaceutical intermediate

Referencestereoisomer of

(-)-norchlorcyclizine

CAS300543-56-0

pharmaceutical intermediate

Referencesame scaffold

Chlorcyclizine hydrochloride

CAS1620-21-9

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Warning
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
Identifiers
IUPAC Name

1-[(4-chlorophenyl)-phenylmethyl]piperazine

InChIKey

UZKBSZSTDQSMDR-UHFFFAOYSA-N

SMILES

C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

Synonyms (34)
  • CBHP
  • Cetirizine EP Impurity A; Hydroxyzine EP Impurity A; Meclozine EP Impurity H
  • Cetirizine EP impurity A
  • Cetirizine impurity A, European Pharmacopoeia (EP)
  • Meclozine impurity H, European Pharmacopoeia (EP)
  • USP CBHP; 1-((4-chlorophenyl)(phenyl)methyl)piperazine
  • (S)-Nor-CCZ
  • 4-chlorobenzhydryl piperazine
  • 98% +(contains <7%H2O)
  • Cetirizine Impurity A
  • Cetirizine impurity A CRS
  • Meclozine impurity H CRS
  • Norchlorcyclizine

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