Home/Compounds/Pharmaceutical Intermediate/(6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carbothioic acid
C24H30F2O5S
468.6 g/mol
Pharmaceutical IntermediateWarning
(6alpha,11beta,16alpha,17alpha)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid
CAS80474-45-9
Category
Pharmaceutical Intermediate
Compound Class
Steroid
Primary Use
Pharmaceutical Intermediate
This compound is a fluorinated corticosteroid intermediate used in the manufacturing of fluticasone propionate. It features a complex polycyclic structure with multiple chiral centers, including alcohol and ester functional groups.
Pharmaceutical intermediate for fluticasone propionate
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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CAS 80474-45-9
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Safety Reference
Warning
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H412Harmful to aquatic life with long lasting effects
Identifiers
IUPAC Name
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioic S-acid
InChIKey
QGESYFOFLPJDJW-CQRCZTONSA-N
SMILES
CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)S
Synonyms (17)
- Fluticasone Impurity 13