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Home/Compounds/API/Fluticasone propionate
C25H31F3O5S
500.6 g/mol
APIDanger

FLUTICASONE PROPIONATE

CAS80474-14-2
Category
API
Compound Class
Steroid
Primary Use
Pharmaceutical Raw Material

Fluticasone propionate is an active pharmaceutical ingredient used in pharmaceutical manufacturing. It is associated with potential developmental toxicity as indicated by government labeling requirements.

pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

Restricted or banned substances

Substances on this list are banned or restricted under the named regulation. This page is a compliance reference — verify your obligations under applicable law.

Relevant lists:California Proposition 65

CAS 80474-14-2

Related Compounds

SimilarStructure SimilarSimilarity 0.80

(6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carbothioic acid

CAS80474-45-9

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.77

Halobetasol propionate

CAS66852-54-8

pharmaceutical raw material

SimilarStructure SimilarSimilarity 0.75

Fluticasone furoate

CAS397864-44-7

pharmaceutical raw material

ReferenceSame Category

Theobromine sodium salicylate

CAS8048-31-5

pharmaceutical raw material

ReferenceSame Category

Acriflavine hydrochloride

CAS8048-52-0

pharmaceutical raw material

ReferenceSame Category

Balsalazide

CAS80573-04-2

pharmaceutical raw material

ReferenceSame Category

Rifaximin

CAS80621-81-4

pharmaceutical raw material

Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life
Regulatory Compliance1
  • California Proposition 65USRegulation
    Listed· listed since 1998-05-15Source

Customs Tariff Classification

The international HS code for FLUTICASONE PROPIONATE (CAS 80474-14-2) is 2937.22.

HS code (international, 6-digit)

2937.22

EU CN code (8-digit)

2937 22 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

InChIKey

WMWTYOKRWGGJOA-CENSZEJFSA-N

SMILES

CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF

Synonyms (108)
  • Fluticasone propionate (JAN/USP)
  • Fluticasone propionate for impurity C identification, EuropePharmacopoeia (EP)
  • Fluticasone propionate for impurity G identification, EuropePharmacopoeia (EP)
  • Fluticasone propionate, European Pharmacopoeia (EP)
  • Fluticasone propionate, United States Pharmacopeia (USP)
  • 24 Hour Allergy Nasal
  • ARMONAIR DIGIHALER
  • Aerivio Spiromax
  • Airflusal forspiro
  • ArmonAir RespiClick
  • ArmonAir RespiClickTM
  • Asmatil
  • Axotide
  • Brethal
  • CHILDRENS FLONASE
  • Childrens Nasopro
  • Cultivate
  • Cutivate
  • Cutivate (TN)
  • FLUTICASONE PROPIONATE
  • FLUTICASONE PROPIONATE DISKUS
  • Flixonase
  • Flixonase Nasal Spray
  • Flixotide
  • Flixotide Disk
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  • Flonase
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  • Fluticasonpropionat Allen
  • Flutide
  • Flutivate
  • Fluxonal
  • HEB Nasopro 24
  • Inalacor
  • Kirkland Signature Aller Flo
  • Nasofan
  • Nasopro 24
  • Pirinase
  • Rinosone
  • Sereflo
  • Seretide 100
  • Seretide 125
  • Seretide 250
  • Seretide 50
  • Seretide 500
  • Sirdupla
  • Skyron
  • Topcare Allergy Relief Nasal
  • Trialona
  • Ubizol
  • Walgreens allergy nasal
  • Welby Fluticasone
  • Xhance
  • Zoflut
  • allergy relief nasal
  • atemur
  • childrens allergy nasal
  • childrens nasal
  • leader allergy relief nasal
  • leader fluticasone propionate