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Home/Compounds/API/O-desmethyl tramadol
C15H23NO2
249.35 g/mol
APIDanger

O-Desmethyltramadol

CAS80456-81-1EC999-177-3
Category
API
Compound Class
Amine
Primary Use
Pharmaceutical Raw Material

O-Desmethyltramadol is a ring assembly and an alkylbenzene. It is one of the major metabolites of tramadol.

pharmaceutical raw materialresearch compound for metabolism studies

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongSame Parent

(+)-O-desmethyl tramadol hydrochloride

CAS148262-77-5

pharmaceutical raw material

StrongSame Parent

O-desmethyl tramadol hydrochloride

CAS185453-02-5

pharmaceutical intermediate

ReferenceSame Category

Saponin

CAS8047-15-2

pharmaceutical raw material

ReferenceSame Category

Fluticasone propionate

CAS80474-14-2

pharmaceutical raw material

ReferenceSame Category

Theobromine sodium salicylate

CAS8048-31-5

pharmaceutical raw material

ReferenceSame Category

Acriflavine hydrochloride

CAS8048-52-0

pharmaceutical raw material

Referencestereoisomer of

O-Desmethyl Tramadol-d6

CAS873928-73-5

research compound

Referencestereoisomer of

(+)-O-DesMethyl TraMadol-D6

CAS1261393-87-6

research compound

Safety Reference

Toxic
Toxic
Harmful
Harmful
Environmental Hazard
Environmental Hazard
Danger
H301Toxic if swallowed
H336May cause drowsiness or dizziness
H411Toxic to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for O-Desmethyltramadol (CAS 80456-81-1) is 2922.50.

HS code (international, 6-digit)

2922.50

EU CN code (8-digit)

2922 50 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol

InChIKey

UWJUQVWARXYRCG-HIFRSBDPSA-N

SMILES

CN(C)C[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)O)O

Synonyms (21)
  • O-DSMT
  • Tramadol EP Impurity D ( and Enantiomer)
  • Desmetramadol
  • Desmetramadol, R,R-(+)-
  • Desmetramadol, cis-(+)-
  • Mono-O-demethyltramadol
  • O-Demethyltramadol
  • O-Desmethyltramadol
  • desmetramadolum
  • tramadol M1 metabolite

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