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Home/Compounds/Pharmaceutical Intermediate/(2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
C20H19NO4
337.4 g/mol
Pharmaceutical IntermediateWarning

Fmoc-Pro-OH

CAS71989-31-6
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Fmoc-Pro-OH is a protected proline derivative widely used as a building block in solid-phase peptide synthesis. Its Fmoc (9-fluorenylmethoxycarbonyl) group allows for temporary protection of the amino function during chain assembly.

Building block for peptide synthesisLaboratory reagent for solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.91

Fmoc-Pro-Pro-OH

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research compound

StrongStructure SimilarSimilarity 0.91

Fmoc-Pro-Pro-Pro-OH

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research compound

SimilarStructure SimilarSimilarity 0.73

2-[[(2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carbonyl]amino]acetic acid

CAS250695-65-9

research compound

ApplicationSame Use

Fmoc-O-tert-butyl-L-tyrosine

CAS71989-38-3

pharmaceutical intermediate

ApplicationSame Use

Fmoc-sarcosine monohydrate

CAS77128-70-2

pharmaceutical intermediate

ApplicationSame Use

Fmoc-N-Methyl-L-alanine

CAS84000-07-7

pharmaceutical intermediate

ApplicationSame Use

N-Fmoc-N'-trityl-D-glutamine

CAS200623-62-7

pharmaceutical intermediate

ReferenceSame Category

Fmoc-O-tert-Butyl-L-serine

CAS71989-33-8

pharmaceutical intermediate

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Safety Reference

Harmful
Harmful
Warning
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for Fmoc-Pro-OH (CAS 71989-31-6) is 2933.99.

HS code (international, 6-digit)

2933.99

EU CN code (8-digit)

2933 99 80

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid

InChIKey

ZPGDWQNBZYOZTI-SFHVURJKSA-N

SMILES

C1C[C@H](N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O

Synonyms (18)
  • FMOC-PRO
  • Fmoc-L-Pro-OH
  • Fmoc-L-proline
  • Fmoc-Pro-OH
  • Fmoc-Pro-OH, >=99.0% (HPLC)
  • Fmoc-Pro-OH,Nonhydrate
  • L-Proline-N-Fmoc
  • N-FMOC-L-PROLINE

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