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Home/Compounds/API/4'-demethylepipodophyllotoxin
C21H20O8
400.4 g/mol
APIDanger

4'-Demethylepipodophyllotoxin

CAS6559-91-7
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material

4'-Demethylepipodophyllotoxin is an organic heterotetracyclic compound that is the 9-epimer of 4'-demethylpodophyllotoxin. It is recognized as an antineoplastic agent and is a member of phenols and furonaphthodioxoles.

antineoplastic agent

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.84

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Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Danger
H315Causes skin irritation
H319Causes serious eye irritation
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child

Customs Tariff Classification

The international HS code for 4'-Demethylepipodophyllotoxin (CAS 6559-91-7) is 2932.20.

HS code (international, 6-digit)

2932.20

EU CN code (8-digit)

2932 20 90

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

InChIKey

YVCVYCSAAZQOJI-JHQYFNNDSA-N

SMILES

COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O

Synonyms (20)
  • Etoposide EP Impurity E
  • Etoposide EP Impurity E; Podophyllotoxin EP Impurity B (4'-Demethyl Epi-Podophyllotoxin (Dmep))
  • 4'-DMEP
  • 4'-Demethylepipodophyllotoxin
  • etoposide aglycone

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