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Home/Compounds/Pharmaceutical Intermediate/N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl]-L-2,4-diaminobutyric acid
C32H38N2O6
546.7 g/mol
Pharmaceutical Intermediate

FMOC-DAB(IVDDE)-OH

CAS607366-21-2
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

FMOC-DAB(IVDDE)-OH is a protected amino acid building block used in peptide synthesis. It features a fluorenylmethyloxycarbonyl (FMOC) protecting group on the amino terminus and an IVDDE protecting group on the side chain, enabling selective deprotection during solid-phase peptide assembly.

protected amino acid building block for peptide synthesisintermediate for pharmaceutical manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.90

N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl]-L-lysine

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SimilarStructure SimilarSimilarity 0.80

(2S)-4-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid

CAS235788-61-1

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.72

N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-lysine

CAS150629-67-7

pharmaceutical intermediate

SimilarStructure SimilarSimilarity 0.72

Fmoc-D-Lys(Dde)-OH

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ApplicationSame Use

N-alpha-Cbz-D-2-4-diaminobutanoic acid

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N-[(1,1-Dimethylethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-D-alanine

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Related Reading

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2026 has been a concentrated year for peptide therapeutics. Efficacy reached a new high in late-stage trials, the obesity field moved beyond the incretins to amylin, the oral route reached weight management, and peptide-guided radioligand therapy kept advancing — each point tied to a specific 2025–2026 result.

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Identifiers
IUPAC Name

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[[1-(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)-3-methylbutylidene]amino]butanoic acid

InChIKey

IMMMALLSYWTSAX-VWLOTQADSA-N

SMILES

CC(C)CC(=NCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)C4=C(CC(CC4=O)(C)C)O

Synonyms (7)
  • FMOC-DAB(IVDDE)-OH
  • Fmoc-L-Dab(ivDde)-OH

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