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Home/Compounds/Pharmaceutical Intermediate/N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-lysine
C31H36N2O6
532.6 g/mol
Pharmaceutical Intermediate

Fmoc-Lys(Dde)-OH

CAS150629-67-7
Category
Pharmaceutical Intermediate
Compound Class
Peptide
Primary Use
Pharmaceutical Intermediate

Fmoc-Lys(Dde)-OH is a protected amino acid derivative used as a building block in solid-phase peptide synthesis. The compound features a fluorenylmethoxycarbonyl (Fmoc) group for N-terminal protection and a Dde group for orthogonal protection of the lysine side chain.

Protected amino acid for peptide synthesisBuilding block for solid-phase peptide synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

StrongStructure SimilarSimilarity 0.89

(2S)-4-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid

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SimilarStructure SimilarSimilarity 0.81

N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl]-L-lysine

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N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl]-L-2,4-diaminobutyric acid

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O1-tert-butyl O3-ethyl cis-4-hydroxypiperidine-1,3-dicarboxylate

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Referencestereoisomer of

Fmoc-D-Lys(Dde)-OH

CAS333973-51-6

pharmaceutical intermediate

Identifiers
IUPAC Name

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[1-(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)ethylideneamino]hexanoic acid

InChIKey

AOHSSQNORWQENF-VWLOTQADSA-N

SMILES

CC(=NCCCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)C4=C(CC(CC4=O)(C)C)O

Synonyms (15)
  • FMOC-L-LYS(DDE)-OH
  • Fmoc-L-Lysine(Dde)-OH
  • Fmoc-Lys(Dde)-OH