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Home/Compounds/Pharmaceutical Intermediate/(S)-GNA-U-phosphoramidite
C37H45N4O7P
688.7 g/mol
Pharmaceutical Intermediate

(S)-GNA-U-phosphoramidite

CAS494784-15-5
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate

(S)-GNA-U-phosphoramidite is a phosphoramidite building block used in oligonucleotide synthesis. It features a uracil nucleobase and a chiral glycol nucleic acid (GNA) backbone, with protective groups including a dimethoxytrityl (DMT) group and a diisopropylamino-cyanoethyl phosphoramidite moiety.

Phosphoramidite building block for oligonucleotide synthesisIntermediate for the production of modified oligonucleotides

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.79

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Identifiers
IUPAC Name

3-[[(2S)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-(2,4-dioxopyrimidin-1-yl)propan-2-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

KZZGGKJIAMPACS-AQXIKWHWSA-N

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H](CN1C=CC(=O)NC1=O)COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC

Synonyms (1)
  • (S)-GNA-U-phosphoramidite