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Home/Compounds/Pharmaceutical Intermediate/(S)-GNA-T-phosphoramidite
C38H47N4O7P
702.8 g/mol
Pharmaceutical Intermediate

(S)-GNA-T-phosphoramidite

CAS168332-13-6
Category
Pharmaceutical Intermediate
Compound Class
Other
Primary Use
Pharmaceutical Intermediate

(S)-GNA-T-phosphoramidite is a protected phosphoramidite building block used in the synthesis of glycerol nucleic acid (GNA) oligonucleotides. It features a thymine base attached to a chiral glycerol backbone with dimethoxytrityl (DMT) and phosphoramidite protecting groups.

Pharmaceutical intermediate for GNA synthesisBuilding block for oligonucleotide manufacturing

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.79

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Referencesame scaffold

1-[(2R)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-hydroxypropyl]-5-methylpyrimidine-2,4-dione

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(S)-DMT-glycidol-T

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Identifiers
IUPAC Name

3-[[(2S)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-(5-methyl-2,4-dioxopyrimidin-1-yl)propan-2-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChIKey

RIVAXSKTYGDAOA-NMIPJSAASA-N

SMILES

CC1=CN(C(=O)NC1=O)C[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)OP(N(C(C)C)C(C)C)OCCC#N

Synonyms (5)
  • (S)-GNA-T-phosphoramidite
  • (S)-T-GNA phosphoramidite
  • T-(S)-GNA phosphoramidite

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