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Home/Compounds/API/Marizomib
C15H20ClNO4
313.77 g/mol
APIDanger

Salinosporamide A

CAS437742-34-2
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material

Salinosporamide A is a naturally occurring compound originally isolated from marine actinobacteria. It is primarily studied as an active pharmaceutical ingredient for its role in inhibiting the proteasome, a key cellular protein-degradation complex.

pharmaceutical research and developmentproteasome inhibition studiesanticancer mechanism research

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Safety Reference

Harmful
Harmful
Health Hazard
Health Hazard
Danger
H315Causes skin irritation
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
Identifiers
IUPAC Name

(1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

InChIKey

NGWSFRIPKNWYAO-SHTIJGAHSA-N

SMILES

C[C@]12[C@H](C(=O)N[C@]1(C(=O)O2)[C@H]([C@H]3CCCC=C3)O)CCCl

Synonyms (12)
  • Marizomib (USAN/INN)
  • Homosalinosporamide A
  • Marizomib?
  • Salinosporamide A;NPI-0052
  • Salinosporin A
  • marizomibum
  • salinosporamide A