C15H20ClNO4
313.77 g/mol
APIDanger
Salinosporamide A
CAS437742-34-2
Category
API
Compound Class
Natural Product
Primary Use
Pharmaceutical Raw Material
Salinosporamide A is a naturally occurring compound originally isolated from marine actinobacteria. It is primarily studied as an active pharmaceutical ingredient for its role in inhibiting the proteasome, a key cellular protein-degradation complex.
pharmaceutical research and developmentproteasome inhibition studiesanticancer mechanism research
Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.
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pharmaceutical raw material
Safety Reference
Danger
H315Causes skin irritation
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
Customs Tariff Classification
The international HS code for Salinosporamide A (CAS 437742-34-2) is 2934.99.
HS code (international, 6-digit)
2934.99
EU CN code (8-digit)
2934 99 90
Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.
Identifiers
IUPAC Name
(1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione
InChIKey
NGWSFRIPKNWYAO-SHTIJGAHSA-N
SMILES
C[C@]12[C@H](C(=O)N[C@]1(C(=O)O2)[C@H]([C@H]3CCCC=C3)O)CCCl
Synonyms (12)
- Marizomib (USAN/INN)
- Homosalinosporamide A
- Marizomib?
- Salinosporamide A;NPI-0052
- Salinosporin A
- marizomibum
- salinosporamide A
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