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Home/Compounds/Pharmaceutical Intermediate/2-Bromo-4'-Benzyloxy-3'-nitroacetophenone
C15H12BrNO4
350.16 g/mol
Pharmaceutical IntermediateDanger

2-bromo-1-(3-nitro-4-phenylmethoxyphenyl)ethanone

CAS43229-01-2EC610-115-3
Category
Pharmaceutical Intermediate
Compound Class
Aromatic
Primary Use
Pharmaceutical Intermediate

This compound is a pharmaceutical intermediate used in the synthesis of formoterol, a beta-2 adrenergic receptor agonist. It features a bromoacetyl group attached to a nitro-substituted aromatic ring with a benzyloxy substituent, reflecting its role in building the formoterol molecular structure.

intermediate in formoterol synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

ReferenceSame Category

N,O-Dibenzylated formoterol

CAS43229-70-5

pharmaceutical intermediate

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pharmaceutical intermediate

ReferenceSame Category

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CAS4330-21-6

pharmaceutical intermediate

ReferenceSame Category

3,5-dichloro-4-nitropyridine

CAS433294-98-5

pharmaceutical intermediate

Safety Reference

Corrosive
Corrosive
Harmful
Harmful
Health Hazard
Health Hazard
Environmental Hazard
Environmental Hazard
Danger
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H370Causes damage to organs
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Customs Tariff Classification

The international HS code for 2-bromo-1-(3-nitro-4-phenylmethoxyphenyl)ethanone (CAS 43229-01-2) is 2914.79.

HS code (international, 6-digit)

2914.79

EU CN code (8-digit)

2914 79 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

2-bromo-1-(3-nitro-4-phenylmethoxyphenyl)ethanone

InChIKey

PBAAKBQGBSUCTG-UHFFFAOYSA-N

SMILES

C1=CC=C(C=C1)COC2=C(C=C(C=C2)C(=O)CBr)[N+](=O)[O-]

Synonyms (9)
  • Formoterol Impurity 10
  • Formoterol Impurity 23

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