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Home/Compounds/Pharmaceutical Intermediate/(R)-pyroglutamic acid
C5H7NO3
129.11 g/mol
Pharmaceutical IntermediateWarning

D-Pyroglutamic acid

CAS4042-36-8EC223-735-0
Category
Pharmaceutical Intermediate
Compound Class
Organic Acid
Primary Use
Pharmaceutical Intermediate

D-Pyroglutamic acid is a chiral derivative of the natural amino acid pyroglutamic acid, formed by the cyclization of glutamic acid. It serves as a pharmaceutical intermediate in the synthesis of various compounds.

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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Related Compounds

SimilarStructure SimilarSimilarity 0.76

(S)-6-Oxo-2-piperidinecarboxylic acid

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pharmaceutical intermediate

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research compound

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(R)-4-Methyloxazolidin-2-one

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pharmaceutical intermediate

ReferenceSame Category

1-(diphenylmethyl)azetidin-3-ol

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pharmaceutical intermediate

ReferenceSame Category

3-Amino-1-diphenylmethylazetidine

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pharmaceutical intermediate

ReferenceSame Category

4-Methoxypiperidine

CAS4045-24-3

pharmaceutical intermediate

Referencestereoisomer of

Magnesium pidolate

CAS62003-27-4

pharmaceutical raw material

Referencestereoisomer of

(S)-pyroglutamic acid

CAS98-79-3

food additive and antioxidant

Safety Reference

Harmful
Harmful
Warning
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Customs Tariff Classification

The international HS code for D-Pyroglutamic acid (CAS 4042-36-8) is 2933.79.

HS code (international, 6-digit)

2933.79

EU CN code (8-digit)

2933 79 00

Classification per the EU customs inventory ECICS (2026-07 snapshot, HS 2022). National tariff lines and product form can affect the final classification.

Identifiers
IUPAC Name

(2R)-5-oxopyrrolidine-2-carboxylic acid

InChIKey

ODHCTXKNWHHXJC-GSVOUGTGSA-N

SMILES

C1CC(=O)N[C@H]1C(=O)O

Synonyms (25)
  • (+)-Pidolic acid
  • (+)-Pyroglutamic acid
  • (R)-pyroglutamic acid
  • 5-oxo-D-proline
  • D-5-Oxoproline
  • D-Glutamic Acid Lactam
  • D-Pidolic acid
  • D-Proline, 5-oxo-
  • D-Pyr-OH
  • D-PyroGlu
  • D-Pyroglutamic acid
  • H-D-Pyr-OH
  • Proline, 5-oxo-, D-
  • RecPGA 100k
  • RecPGA 373K
  • Vonoprazan Impurity 289
  • pyroglutaminsaure

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