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Home/Compounds/Pharmaceutical Intermediate/Lithium bis(trimethylsilyl)amide
C6H19LiNSi2
168.4 g/mol
Pharmaceutical IntermediateDanger

Bis(trimethylsilyl)amidolithium

CAS4039-32-1EC223-725-6
Category
Pharmaceutical Intermediate
Compound Class
Organometallic
Primary Use
Pharmaceutical Intermediate

Bis(trimethylsilyl)amidolithium is a lithium salt of the bis(trimethylsilyl)amide anion. It is commonly used as a strong, non-nucleophilic base and a source of the bis(trimethylsilyl)amide ligand in organic synthesis and pharmaceutical manufacturing.

pharmaceutical intermediatestrong base in organic synthesis

Content scope: Information here supports chemical identification and industrial supply, research, and manufacturing contexts. It is not a therapeutic claim, medical advice, or drug-use instructions.

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CAS 4039-32-1

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Safety Reference

Flammable
Flammable
Corrosive
Corrosive
Harmful
Harmful
Environmental Hazard
Environmental Hazard
Danger
H228Flammable solid
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H332Harmful if inhaled
H412Harmful to aquatic life with long lasting effects
Identifiers
InChIKey

QQIRAVWVGBTHMJ-UHFFFAOYSA-N

SMILES

[Li].C[Si](C)(C)N[Si](C)(C)C

Synonyms (12)
  • (LiN(SiMe3)2)
  • Li bis(TMS)A
  • Lithium hexamethyldisilazane
  • lithium HMDS
  • lithium hexamethydisilazane
  • lithium hexamethyidisilazane